Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
TSEPA Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
27415-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSEPA Fusion Protein Ag26387 (61-222 aa encoded by BC130516)
Conjugate
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AEICEQIEG CESLQPFELP MNFPGLFKIV ADKTPYLTME EITRTIHIGP SRLGHPCFYH QKDIKLENLI IKQGEQIMLN SVEEIDGEIM VSCAVARNHQ THSFNLPLSQ EGEFYECEDE RIYTLKEIVE WKIPKNRTRT VNLTDFSNKW DSTNPFPKDF YGT (61-222 aa encoded by BC130516)
Target Information
Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: bA325O24.3; bA325O24.4; FLJ40584; Gasp; GRB2-associated protein; Grb2-associating protein; MGC163388; Protein THEMIS; Protein thylex; signaling phosphoprotein specific for T cells; thymocyte expressed molecule involved in selection; thymocyte selection pathway associated; Thymocyte-expressed molecule involved in selection
Gene Aliases: C6orf190; C6orf207; E430004N04Rik; GASP; SPOT; THEMIS; thylex; TSEPA
UniProt ID: (Human) Q8N1K5, (Mouse) Q8BGW0
Entrez Gene ID: (Human) 387357, (Mouse) 210757
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support