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Product Details
17566-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TSGA14 Fusion Protein Ag11764 (1-301 aa encoded by BC056162)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSLRRHIGN PEYLMKRIPQ NPRYQHIKSR LDTGNSMTKY TEKLEEIKKN YRYKKDELFK RLKVTTFAQL IIQVASLSDQ TLEVTAEEIQ RLEDNDSAAS DPDAETTART NGKGNPGEQS PSPEQFINNA GAGDSSRSTL QSVISGVGEL DLDKGPVKKA EPHTKDKPYP DCPFLLLDVR DRDSYQQCHI VGAYSYPIAT LSRTMNPYSN DILEYKNAHG KIIILYDDDE RLASQAATTM CERGFENLFM LSGGRLNQAN SSGRESKVPG ARSAQNLPGG GPASHSNPRS LSSGHLQGKP WK (1-301 aa encoded by BC056162)
Target Information
Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The CEP41 (centrosomal protein of 41 kDa) gene encodes a protein of 373 amino acids that is alternatively spliced into 4 isoforms. Isoforms 1 and 4 are expressed in testis, as well as in and fetal brain and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centrosomal protein 41 kDa; centrosomal protein 41kDa; Centrosomal protein of 41 kDa; Cep41; testis specific gene A14; testis specific protein A14; testis specific, 14; Testis-specific gene A14 protein
Gene Aliases: 1700017E11Rik; 2810431D15Rik; CEP41; JBTS15; TSGA14
UniProt ID: (Human) Q9BYV8, (Mouse) Q99NF3, (Rat) Q4KM37
Entrez Gene ID: (Human) 95681, (Mouse) 83922, (Rat) 500069
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