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Immunogen sequence: NGTNPDAASR AIDYVQRQLH CCGIHNYSDW ENTDWFKETK NQSVPLSCCR ETASNCNGSL AHPSDLYAEG CEALVVKKLQ EI
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: tetraspan 3; tetraspan TM4SF; Tetraspanin TM4-A; Tetraspanin-3; Transmembrane 4 superfamily member 8; Tspan-3
Gene Aliases: TM4-A; TM4SF8; TSPAN-3; TSPAN3
UniProt ID: (Human) O60637
Entrez Gene ID: (Human) 10099
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