Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAGVSACIKY SMFTFNFLFW LCGILILALA IWVRISNDSQ AIFGSEDVGS SSYVAVDILI AVGAIIMILG FLACCGAIKE SRCMLLLFFI GLLLILLLQV ATGILGAVFK SKSDRIVNET LYENTKLLSA TGESEKQFQE AIIVFQEEFK CCGLVNGAAD WGNNFQHYPE LCACLDKQRP CQSYNGKQVY KETCISFIKD FLAKNLIIVI GIAFGLAVIE ILGLVFSMVL YCQIGNK
TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Tetraspanin-8; Tetraspanin8; Transmembrane 4 superfamily member 3; Tspan-8; Tumor-associated antigen CO-029
Gene Aliases: CO-029; TM4SF3; TSPAN8
UniProt ID: (Human) P19075
Entrez Gene ID: (Human) 7103
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