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Product Details
H00083983-M02A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
6F5
Immunogen
TSSK6 (AAH14611, 174 a.a. approximately 273 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: SAAYASPEVL LGIPYDPKKY DVWSMGVVLY VMVTGCMPFD DSDIAGLPRR QKRGVLYPEG LELSERCKAL IAELLQFSPS ARPSAGQVAR NCWLRAGDSG
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cancer/testis antigen 72; CT72; serine/threonine protein kinase SSTK; Serine/threonine-protein kinase SSTK; Small serine/threonine kinase; testis secretory sperm-binding protein Li 205a; testis-specific serine kinase 6; Testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK6
Gene Aliases: CT72; FKSG82; SSTK; TSSK4; TSSK6
UniProt ID: (Human) Q9BXA6
Entrez Gene ID: (Human) 83983
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