Proteintech

TST Polyclonal Antibody

TST Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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TST Antibody (16311-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human colon cancer using 16311-1-AP (TST antibody) at dilution of 1:50 (under 40x lens).

TST Antibody in Immunoprecipitation (IP)

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Product Details

16311-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 8 publications 8 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TST Fusion Protein Ag9346 (1-297 aa encoded by BC010148)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.28 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MVHQVLYRA LVSTKWLAES IRTGKLGPGL RVLDASWYSP GTREARKEYL ERHVPGASFF DIEECRDTAS PYEMMLPSEA GFAEYVGRLG ISNHTHVVVY DGEHLGSFYA PRVWWMFRVF GHRTVSVLNG GFRNWLKEGH PVTSEPSRPE PAVFKATLDR SLLKTYEQVL ENLESKRFQL VDSRSQGRFL GTEPEPDAVG LDSGHIRGAV NMPFMDFLTE DGFEKGPEEL RALFQTKKVD LSQPLIATCR KGVTACHVAL AAYLCGKPDV AVYDGSWSEW FRRAPPESRV SQGKSEKA (1-297 aa encoded by BC010148)

Target Information

The product of this gene is a mitochondrial matrix enzyme that is encoded by the nucleus. It may play roles in cyanide detoxification, the formation of iron-sulfur proteins, and the modification of sulfur-containing enzymes. The gene product contains two highly conservative domains (rhodanese homology domains), suggesting these domains have a common evolutionary origin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway.

Frontiers in pharmacology

Katsouda A,Markou M,Zampas P,Varela A,Davos CH,Vellecco V,Cirino G,Bucci M,Papapetropoulos A

Fri Mar 03 00:00:00 UTC 2023

Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.

Human molecular genetics

González-García P,Hidalgo-Gutiérrez A,Mascaraque C,Barriocanal-Casado E,Bakkali M,Ziosi M,Abdihankyzy UB,Sánchez-Hernández S,Escames G,Prokisch H,Martín F,Quinzii CM,López LC

Wed Nov 25 00:00:00 UTC 2020

Cystathionine-γ-lyase (CSE) deficiency increases erythropoiesis and promotes mitochondrial electron transport via the upregulation of coproporphyrinogen III oxidase and consequent stimulation of heme biosynthesis.

Biochemical pharmacology

Módis K,Ramanujam VS,Govar AA,Lopez E,Anderson KE,Wang R,Szabo C

Fri Nov 01 00:00:00 UTC 2019

New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H₂S-donor.

Amino acids

Jurkowska H,Wróbel M,Szlęzak D,Jasek-Gajda E

Fri Jun 01 00:00:00 UTC 2018

New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H₂S-donor.

Amino acids

Jurkowska H,Wróbel M,Szlęzak D,Jasek-Gajda E

Fri Jun 01 00:00:00 UTC 2018

Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway.

EMBO molecular medicine

Ziosi M,Di Meo I,Kleiner G,Gao XH,Barca E,Sanchez-Quintero MJ,Tadesse S,Jiang H,Qiao C,Rodenburg RJ,Scalais E,Schuelke M,Willard B,Hatzoglou M,Tiranti V,Quinzii CM

Sun Jan 01 00:00:00 UTC 2017

Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway.

EMBO molecular medicine

Ziosi M,Di Meo I,Kleiner G,Gao XH,Barca E,Sanchez-Quintero MJ,Tadesse S,Jiang H,Qiao C,Rodenburg RJ,Scalais E,Schuelke M,Willard B,Hatzoglou M,Tiranti V,Quinzii CM

Sun Jan 01 00:00:00 UTC 2017

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.

EMBO molecular medicine

Luna-Sánchez M,Hidalgo-Gutiérrez A,Hildebrandt TM,Chaves-Serrano J,Barriocanal-Casado E,Santos-Fandila Á,Romero M,Sayed RK,Duarte J,Prokisch H,Schuelke M,Distelmaier F,Escames G,Acuña-Castroviejo D,López LC

Sun Jan 01 00:00:00 UTC 2017

CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome.

EMBO molecular medicine

Sun Jan 01 00:00:00 UTC 2017

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.

Amino acids

Jurkowska H,Roman HB,Hirschberger LL,Sasakura K,Nagano T,Hanaoka K,Krijt J,Stipanuk MH

Thu May 01 00:00:00 UTC 2014

Primary hepatocytes from mice lacking cysteine dioxygenase show increased cysteine concentrations and higher rates of metabolism of cysteine to hydrogen sulfide and thiosulfate.

Amino acids

Jurkowska H,Roman HB,Hirschberger LL,Sasakura K,Nagano T,Hanaoka K,Krijt J,Stipanuk MH

Thu May 01 00:00:00 UTC 2014

The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.

Antioxidants & redox signaling

Roman HB,Hirschberger LL,Krijt J,Valli A,Kožich V,Stipanuk MH

Sun Oct 20 00:00:00 UTC 2013

The cysteine dioxgenase knockout mouse: altered cysteine metabolism in nonhepatic tissues leads to excess H2S/HS(-) production and evidence of pancreatic and lung toxicity.

Antioxidants & redox signaling

Roman HB,Hirschberger LL,Krijt J,Valli A,Kožich V,Stipanuk MH

Sun Oct 20 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: LL22NC01-146D10.3; MGC19578; Rhodanese; Thiosulfate sulfurtransferase; thiosulfate sulfurtransferase (rhodanese); thiosulfate sulfurtransferase, mitochondrial; Thiosulfate sulphurtransferase (rhodanese)

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Gene Aliases: RDS; RHODAN; Rhodanese; TST

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UniProt ID: (Human) Q16762, (Rat) P24329, (Mouse) P52196

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Entrez Gene ID: (Human) 7263, (Rat) 25274, (Mouse) 22117

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Function(s)

thiosulfate sulfurtransferase activity 5S rRNA binding RNA binding transferase activity

Process(es)

cyanate catabolic process epithelial cell differentiation rRNA import into mitochondrion rRNA transport iron-sulfur cluster assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TST Polyclonal Antibody

TST Antibody (16311-1-AP) in IHC (P)

Product Details

16311-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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