Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (92%), Rat (92%), Chicken (82%), Rhesus Monkey (98%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-5 epimerase/4-reductase; FX protein; GDP-4-keto-6-deoxy-D-mannose epimerase-reductase; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GDP-L-fucose synthase; GDP-L-fucose synthetase; Protein FX; Red cell NADP(H)-binding protein; short chain dehydrogenase/reductase family 4E, member 1; Short-chain dehydrogenase/reductase family 4E member 1; testis tissue sperm-binding protein Li 45a; tissue specific transplantation antigen 3
Gene Aliases: FX; GFUS; P35B; SDR4E1; TSTA3
UniProt ID: (Human) Q13630, (Chinese hamster) Q8K3X2
Entrez Gene ID: (Human) 7264, (Chinese hamster) 100689348
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