Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: STFPSYMAEG ERLYLCGEFS KAAQSFSNAL YLQDGDKNCL VARSKCFLKM GDLERSLKDA EASLQSDPAF CKGILQKAET LYTMGDFE
This gene encodes a tetratricopeptide repeat domain-containing protein that localizes to ciliary axonmenes and plays a role in the docking of the outer dynein arm to cilia. Mutations in this gene cause severely reduced ciliary motility and the disorder CILD35 (ciliary dyskinesia, primary, 35). Primary ciliary dyskinesia is often associated with recurrent respiratory infections, immotile spermatozoa, and situs inversus; an inversion in left-right body symmetry. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Outer dynein arm-docking complex subunit 4; Tetratricopeptide repeat protein 25; TPR repeat protein 25
Gene Aliases: ODAD4; TTC25
UniProt ID: (Human) Q96NG3
Entrez Gene ID: (Human) 83538
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support