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Recommended positive controls: Raji, K562, THP-1, NCI-H929, 293T transfected recombinant TTC39B protein.
Predicted reactivity: Mouse (90%), Rat (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Regulates high density lipoprotein (HDL) cholesterol metabolism by promoting the ubiquitination and degradation of the oxysterols receptors LXR (NR1H2 and NR1H3). [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Tetratricopeptide repeat protein 39B; TPR repeat protein 39B
Gene Aliases: C9orf52; TTC39B
UniProt ID: (Human) Q5VTQ0
Entrez Gene ID: (Human) 158219
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