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Invitrogen
TTC40 Polyclonal Antibody
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Product Details
PA5-58104
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TTC40. Recombinant protein control fragment (Product #RP-97213).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649076
Product Specific Information
Immunogen sequence: LAPDAFQIVL DSENEAKVST GKNRGRFTYL CAKAWHHTVS VDKAAGHLRR LGNENDKERI QIWAELAKVA RKQ
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.
Target Information
The TTC40 gene, which stands for Tetratricopeptide repeat domain 40, is a member of the TPR protein family characterized by highly conserved motifs that facilitate protein-protein interactions. This gene plays a significant role in various cellular processes, including signal transduction and protein assembly. TTC40 has been identified as a novel methylated gene in nasopharyngeal carcinoma, where its expression is significantly reduced in tumor tissues due to hypermethylation. This epigenetic alteration suggests a potential role of TTC40 in tumorigenesis, possibly acting as a tumor suppressor. The decreased expression of TTC40 in cancerous tissues highlights its importance in maintaining cellular homeostasis and integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cilia- and flagella-associated protein 46; protein CFAP46; tetratricopeptide repeat domain 40; Tetratricopeptide repeat protein 40; TPR repeat-containing protein C10orf93
Gene Aliases: bA288G11.4; bA288G11.5; bB137A17.2; bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93; CFAP46; TTC40
UniProt ID: (Human) Q8IYW2
Entrez Gene ID: (Human) 54777
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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