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Invitrogen
TTC8 Polyclonal Antibody
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TTC8 Antibody (PA5-143970) in WB
Western blot analysis of BBS8/TTC8 using BBS8/TTC8 antibody (Product # PA5-143970). Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human SH-SY5Y whole cell lysates; Lane 2: human Hela whole cell lysates; Lane 3: human T-47D whole cell lysates; Lane 4: human SiHa whole cell lysates; Lane 5: rat ovary tissue lysates; Lane 6: rat PC-12 whole cell lysates; Lane 7: mouse ovary tissue l... View More
Product Details
PA5-143970
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human BBS8/TTC8 recombinant protein (Position: E271-Q533).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_3075184
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human SH-SY5Y whole cell, human Hela whole cell, human T-47D whole cell, human SiHa whole cell, rat ovary tissue, rat PC-12 whole cell, mouse ovary tissue, mouse NIH/3T3 whole cell. Flow: RT4 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 8 protein; Bardet-Biedl syndrome 8 protein homolog; Bardet-Biedl syndrome type 8; Tetratricopeptide repeat protein 8; TPR repeat protein 8
Gene Aliases: 0610012F22Rik; AV001447; BBS8; RP51; TTC8
UniProt ID: (Human) Q8TAM2, (Mouse) Q8VD72
Entrez Gene ID: (Human) 123016, (Rat) 299246, (Mouse) 76260
axon guidance
sensory perception of smell
biological_process
olfactory bulb development
regulation of protein localization
nonmotile primary cilium assembly
multicellular organism growth
cilium assembly
fat cell differentiation
establishment of anatomical structure orientation
regulation of stress fiber assembly
camera-type eye photoreceptor cell differentiation
renal tubule development
protein transport
sensory processing
transport
cell projection organization
negative regulation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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