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Product Details
PA5-56269
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TTI2. Recombinant protein control fragment (Product #RP-93783).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649091
Product Specific Information
Immunogen sequence: QEDSNLSEEL SHSAFGQAFS KILHCLARPE ARRGNVKDAV LKDLGDLIEA TGFDRLFEGT GARLRGMPET LGQVAKALEK Y
Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 57%.
Target Information
The DNA replication (origin) licensing system is necessary for duplicating the genome in each cell cycle. Geminin is a protein that prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during G1 phase and accumulates during S, G2, and M phases of mitosis. It is then degraded during the metaphase-anaphase trasition allowing replication to occur during subsequent cycles. Geminin has also been implicated in maintaining integrity of the male germline genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ23263; Tel2 interacting protein 2 homolog; TELO2-interacting protein 2
Gene Aliases: C8orf41; MRT39; TTI2
UniProt ID: (Human) Q6NXR4
Entrez Gene ID: (Human) 80185
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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