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Proteintech
TTK Polyclonal Antibody
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Product Details
10381-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TTK Fusion Protein Ag0405 (536-789 aa encoded by BC000633)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SSKVFQVLN EKKQIYAIKY VNLEEADNQT LDSYRNEIAY LNKLQQHSDK IIRLYDYEIT DQYIYMVMEC GNIDLNSWLK KKKSIDPWER KSYWKNMLEA VHTIHQHGIV HSDLKPANFL IVDGMLKLID FGIANQMQPD TTSVVKDSQV GTVNYMPPEA IKDMSSSREN GKSKSKISPK SDVWSLGCIL YYMTYGKTPF QQIINQISKL HAIIDPNHEI EFPDIPEKDL QDVLKCCLKR DPKQRISIPE LLAHP (536-789 aa encoded by BC000633)
Target Information
TTK is a serine/threonine kinase closely related to SPK1, PIM 1 and CDC2 serine/threonine kinases. TTK is a dual-specificity kinase, which can also phosphorylate tyrosine. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. TTK encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cancer/testis antigen 96; Dual specificity protein kinase TTK; monopolar spindle 1 kinase; monopolar spindle 1-like 1; OTTHUMP00000016778; OTTHUMP00000220743; phosphotyrosine picked threonine kinase; Phosphotyrosine picked threonine-protein kinase; PYT
Gene Aliases: CT96; ESK; MPH1; MPS1; MPS1L1; PYT; TTK
UniProt ID: (Human) P33981
Entrez Gene ID: (Human) 7272
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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