Invitrogen

TTLL11 Polyclonal Antibody

1 Published Figure

2 References

View all (2) TTLL11 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (1)

FIGURE: 1 / 2

TTLL11 Antibody (PA5-46070) in WB

Western blot analysis of human THP-1 cell lysate using an anti-TTLL11 polyclonal antibody (Product # PA5-46070).

TTLL11 Antibody in Immunocytochemistry (ICC/IF)

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Product Details

PA5-46070

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human TTLL11 (aa 169-218).

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2606522

Product Specific Information

Peptide sequence: QVLQRPPPTL PPSKPKPVQG LCPHGKPRDK GRSCKRSSGH GSGENGSQRP

Sequence homology: Human: 100%; Rabbit: 92%

Target Information

TTLL11 is a polyglutamase which preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. TTLL11 is required for CCSAP localization to both spindle and cilia microtubules.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family.

Scientific reports

Mathieu H,Patten SA,Aragon-Martin JA,Ocaka L,Simpson M,Child A,Moldovan F

PA5-46070 was used in Immunocytochemistry to identify an insertion in the tubulin tyrosine ligase like gene as the causative gene of idiopathic scoliosis in a British family.

Wed May 26 00:00:00 UTC 2021

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family.

Scientific reports

Mathieu H,Patten SA,Aragon-Martin JA,Ocaka L,Simpson M,Child A,Moldovan F

PA5-46070 was used in Immunocytochemistry to identify an insertion in the tubulin tyrosine ligase like gene as the causative gene of idiopathic scoliosis in a British family.

Wed May 26 00:00:00 UTC 2021

Genetic variant of TTLL11 gene and subsequent ciliary defects are associated with idiopathic scoliosis in a 5-generation UK family.

Scientific reports

Mathieu H,Patten SA,Aragon-Martin JA,Ocaka L,Simpson M,Child A,Moldovan F

PA5-46070 was used in Immunocytochemistry to identify an insertion in the tubulin tyrosine ligase like gene as the causative gene of idiopathic scoliosis in a British family.

Wed May 26 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: Tubulin polyglutamylase TTLL11; tubulin tyrosine ligase like11; tubulin tyrosine ligase-like family member 11; tubulin tyrosine ligase-like family, member 11; Tubulin--tyrosine ligase-like protein 11

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Gene Aliases: bA244O19.1; C9orf20; TTLL11

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UniProt ID: (Human) Q8NHH1

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Entrez Gene ID: (Human) 158135

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Function(s)

ATP binding ligase activity

Process(es)

protein polyglutamylation microtubule severing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TTLL11 Polyclonal Antibody

TTLL11 Antibody (PA5-46070) in WB

Product Details

PA5-46070

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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