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Proteintech
TUB Polyclonal Antibody
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Product Details
17928-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TUB Fusion Protein Ag12354 (212-561 aa encoded by BC075032)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GQSDHAQDA GETAAGGGER PSGQDLRATM QRKGISSSMS FDEDEEDEEE NSSSSSQLNS NTRPSSATSR KSVREAASAP SPTAPEQPVD VEVQDLEEFA LRPAPQGITI KCRITRDKKG MDRGMYPTYF LHLDREDGKK VFLLAGRKRK KSKTSNYLIS VDPTDLSRGG DSYIGKLRSN LMGTKFTVYD NGVNPQKASS STLESGTLRQ ELAAVCYETN VLGFKGPRKM SVIVPGMNMV HERVSIRPRN EHETLLARWQ NKNTESIIEL QNKTPVWNDD TQSYVLNFHG RVTQASVKNF QIIHGNDPDY IVMQFGRVAE DVFTMDYNYP LCALQAFAIA LSSFDSKLAC E (212-561 aa encoded by BC075032)
Target Information
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: retinal degeneration 5; tubby homolog; tubby homologue; Tubby protein; Tubby protein homolog
Gene Aliases: Rd5; RDOB; TUB
UniProt ID: (Human) P50607, (Mouse) P50586, (Rat) O88808
Entrez Gene ID: (Human) 7275, (Mouse) 22141, (Rat) 25609
phagocytosis
phagocytosis, recognition
sensory perception of sound
photoreceptor cell maintenance
positive regulation of phagocytosis
response to stimulus
retina development in camera-type eye
receptor localization to nonmotile primary cilium
protein localization to ciliary membrane
protein localization to photoreceptor outer segment
phototransduction
detection of visible light
response to hormone
multicellular organismal macromolecule metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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