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Product Details
BS-20496R-A647
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TUBA1A & TUBA1B (amino acids 401-451).
Conjugate
Excitation/Emission Max
650/671 nm
View spectra
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha tubulin; Alpha-tubulin 1; Alpha-tubulin 2; Alpha-tubulin 3; Alpha-tubulin isotype M-alpha-1; Alpha-tubulin isotype M-alpha-2; Alpha-tubulin ubiquitous; hum-a-tub1; hum-a-tub2; Talpha1 alpha-tubulin; TUBA1A; TUBA1B; Tubulin alpha-1 chain; Tubulin alpha-1A chain; Tubulin alpha-1B chain; Tubulin alpha-2 chain; Tubulin alpha-3 chain; Tubulin alpha-ubiquitous chain; Tubulin B-alpha-1; Tubulin K-alpha-1; tubulin, alpha 1; tubulin, alpha 1a; tubulin, alpha 1b; tubulin, alpha 2; tubulin, alpha, brain-specific; tubulin, alpha, ubiquitous
Gene Aliases: B-ALPHA-1; K-ALPHA-1; LIS3; RGD1565476; Tuba-1; Tuba1; TUBA1A; TUBA1B; Tuba2; TUBA3
UniProt ID: (Human) Q71U36, (Human) P68363, (Mouse) P68369, (Rat) P68370, (Mouse) P05213, (Rat) Q6P9V9
Entrez Gene ID: (Human) 7846, (Human) 10376, (Mouse) 22142, (Rat) 64158, (Mouse) 22143, (Rat) 500929
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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