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Abnova
TUBGCP4 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 4
TUBGCP4 Antibody (H00027229-B01P) in WB
Western Blot analysis of TUBGCP4 expression in transfected 293T cell line (H00027229-T01) by TUBGCP4 MaxPab polyclonal antibody.
Lane 1: TUBGCP4 transfected lysate(73.26 KDa).
Lane 2: Non-transfected lysate.
Lane 1: TUBGCP4 transfected lysate(73.26 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00027229-B01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TUBGCP4 (NP_055259.2, 1 a.a. approximately 666 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MIHELLLALS GYPGSIFTWN KRSGLQVSQD FPFLHPSETS VLNRLCRLGT DYIRFTEFIE QYTGHVQQQD HHPSQQGQGG LHGIYLRAFC TGLDSVLQPY RQALLDLEQE FLGDPHLSIS HVNYFLDQFQ LLFPSVMVVV EQIKSQKIHG CQILETVYKH SCGGLPPVRS ALEKILAVCH GVMYKQLSAW MLHGLLLDQH EEFFIKQGPS SGNVSAQPEE DEEDLGIGGL TGKQLRELQD LRLIEEENML APSLKQFSLR VEILPSYIPV RVAEKILFVG ESVQMFENQN VNLTRKGSIL KNQEDTFAAE LHRLKQQPLF SLVDFEQVVD RIRSTVAEHL WKLMVEESDL LGQLKIIKDF YLLGRGELFQ AFIDTAQHML KTPPTAVTEH DVNVAFQQSA HKVLLDDDNL LPLLHLTIEY HGKEHKDATQ AREGPSRETS PREAPASGWA ALGLSYKVQW PLHILFTPAV LEKYNVVFKY LLSVRRVQAE LQHCWALQMQ RKHLKSNQTD AIKWRLRNHM AFLVDNLQYY LQVDVLESQF SQLLHQINST RDFESIRLAH DHFLSNLLAQ SFILLKPVFH CLNEILDLCH SFCSLVSQNL GPLDERGAAQ LSILVKGFSR QSSLLFKILS SVRNHQINSD LAQLLLRLDY NKYYTQAGGT LGSFGM
Target Information
The gamma-Tubulin complex is composed of gamma Tubulin and the gamma-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which are essential components of microtubule organizing centers. gamma-Tubulin complex components are localized to both the centrosome, where they are involved in microtubule nucleation, and to the cytoplasm, where they exist as soluble complexes that can be recruited to the centrosome as needed. Although the GCP proteins are related, they have distinct roles which contribute to the proper function of the gamma-Tubulin complex. GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a ubiquitously expressed 667 amino acid member of the gamma-Tubulin complex that localizes to the metaphase spindle during mitosis. In response to proteosome inhibition, GCP4 exhibits increased accumulation at the pericentiolar material where it participates in microtubule organization and nucleation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: gamma tubulin ring complex protein; gamma tubulin ring complex protein (76p gene); Gamma-ring complex protein 76 kDa; Gamma-tubulin complex component 4; GCP-4; h76p; hGCP4; hGrip76; tubulin, gamma complex associated protein 4
Gene Aliases: 4932441P04Rik; 76P; D2Ertd435e; GCP-4; GCP4; Grip76; MCCRP3; TUBGCP4
UniProt ID: (Human) Q9UGJ1, (Mouse) Q9D4F8
Entrez Gene ID: (Human) 27229, (Mouse) 51885
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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