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TUFM Polyclonal Antibody

TUFM Antibody in Immunocytochemistry (ICC/IF)

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TUFM Antibody (26730-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA ) fixed HepG2 cells using 26730-1-AP (TUFM antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

26730-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Zebrafish

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TUFM Fusion Protein Ag24981 (108-455 aa encoded by BC010041)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GITINAAHV EYSTAARHYA HTDCPGHADY VKNMITGTAP LDGCILVVAA NDGPMPQTRE HLLLARQIGV EHVVVYVNKA DAVQDSEMVE LVELEIRELL TEFGYKGEET PVIVGSALCA LEGRDPELGL KSVQKLLDAV DTYIPVPARD LEKPFLLPVE AVYSVPGRGT VVTGTLERGI LKKGDECELL GHSKNIRTVV TGIEMFHKSL ERAEAGDNLG ALVRGLKRED LRRGLVMVKP GSIKPHQKVE AQVYILSKEE GGRHKPFVSH FMPVMFSLTW DMACRIILPP EKELAMPGED LKFNLILRQP MILEKGQRFT LRDGNRTIGT GLVTNTLAMT EEEKNIKWG (108-455 aa encoded by BC010041)

Target Information

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.

The Science of the total environment

Li D,Zhao Q,Xie L,Wang C,Tian Z,Tang H,Xia T,Wang A

Sat Apr 15 00:00:00 UTC 2023

Ablation of Mto1 in zebrafish exhibited hypertrophic cardiomyopathy manifested by mitochondrion RNA maturation deficiency.

Nucleic acids research

Zhang Q,He X,Yao S,Lin T,Zhang L,Chen D,Chen C,Yang Q,Li F,Zhu YM,Guan MX

Fri May 07 00:00:00 UTC 2021

Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism.

Nucleic acids research

Chen D,Zhang Z,Chen C,Yao S,Yang Q,Li F,He X,Ai C,Wang M,Guan MX

Tue Jun 04 00:00:00 UTC 2019

Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function.

Nucleic acids research

Zhang Q,Zhang L,Chen D,He X,Yao S,Zhang Z,Chen Y,Guan MX

Fri Nov 16 00:00:00 UTC 2018

Deletion of Mtu1 (Trmu) in zebrafish revealed the essential role of tRNA modification in mitochondrial biogenesis and hearing function.

Nucleic acids research

Zhang Q,Zhang L,Chen D,He X,Yao S,Zhang Z,Chen Y,Guan MX

Fri Nov 16 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: EF-Tu; Elongation factor Tu, mitochondrial; P43; tufm {ECO:0000250|UniProtKB:P49411}

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Gene Aliases: 2300002G02Rik; C76308; C76389; COXPD4; EF-TuMT; EFTU; P43; TUFM

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UniProt ID: (Human) P49411, (Mouse) Q8BFR5, (Rat) P85834

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Entrez Gene ID: (Human) 7284, (Mouse) 233870, (Rat) 293481

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Function(s)

translation elongation factor activity GTPase activity protein binding GTP binding poly(A) RNA binding nucleotide binding

Process(es)

translation translational elongation mitochondrial translational elongation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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TUFM Polyclonal Antibody

TUFM Antibody (26730-1-AP) in ICC/IF

Product Details

26730-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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