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Invitrogen
TUP1 Monoclonal Antibody (10)
Product Details
MA1-12683
Product Specifications
Species Reactivity
Yeast
Host/Isotype
Mouse
/ IgG
Class
Monoclonal
Type
Antibody
Clone
10
Immunogen
Recombinant protein corresponding to the residues 1-200 of yeast TUP1 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1088117
Product Specific Information
A suggested positive control for this product is Mav108 cells expressing recombinant TUP1 protein.
Target Information
TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Flocculation suppressor protein; General transcriptional corepressor TUP1; Glucose repression regulatory protein TUP1; Repressor AER2; Tup1p
Gene Aliases: AAR1; AER2; AMM1; CRT4; CYC9; FLK1; ROX4; SFL2; TUP1; UMR7; YCR084C; YCR84C
UniProt ID: (Baker's yeast) P16649
Entrez Gene ID: (Baker's yeast) 850445
negative regulation of transcription from RNA polymerase II promoter by glucose
negative regulation of mating-type specific transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of transcription from RNA polymerase II promoter during mitosis
nucleosome positioning
negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter
histone exchange
regulation of transcription from RNA polymerase II promoter in response to osmotic stress
regulation of transcription from RNA polymerase II promoter in response to hypoxia
regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter
regulation of response to DNA damage stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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