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Product Details
H00011344-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TWF2 (NP_009215.1, 1 a.a. approximately 349 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAHQTGIHAT EELKEFFAKA RAGSVRLIKV VIEDEQLVLG ASQEPVGRWD QDYDRAVLPL LDAQQPCYLL YRLDSQNAQG FEWLFLAWSP DNSPVRLKML YAATRATVKK EFGGGHIKDE LFGTVKDDLS FAGYQKHLSS CAAPAPLTSA ERELQQIRIN EVKTEISVES KHQTLQGLAF PLQPEAQRAL QQLKQKMVNY IQMKLDLERE TIELVHTEPT DVAQLPSRVP RDAARYHFFL YKHTHEGDPL ESVVFIYSMP GYKCSIKERM LYSSCKSRLL DSVEQDFHLE IAKKIEIGDG AELTAEFLYD EVHPKQHAFK QAFAKPKGPG GKRGHKRLIR GPGENGDDS
Target Information
TWF2 encodes a protein that was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin, a conserved actin monomer-binding protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A6 related protein; A6-related protein; hA6RP; Protein tyrosine kinase 9-like; protein tyrosine kinase 9-like (A6-related protein); PTK 9L; PTK9L protein tyrosine kinase 9-like (A6-related protein); TWF 2; Twinfilin 2; twinfilin actin-binding protein 2; twinfilin, actin-binding protein, homolog 2; Twinfilin-1-like protein; Twinfilin-2; Twinfilin2
Gene Aliases: A6r; A6RP; MSTP011; PTK9L; TWF2
UniProt ID: (Human) Q6IBS0
Entrez Gene ID: (Human) 11344
positive regulation of lamellipodium assembly
positive regulation of neuron projection development
cell projection organization
negative regulation of actin filament polymerization
regulation of microvillus length
regulation of actin cytoskeleton organization
sequestering of actin monomers
positive regulation of axon extension
barbed-end actin filament capping
cellular response to retinoic acid
cellular response to growth factor stimulus
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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