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Product Details
PA5-62858
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TWF2. Recombinant protein control fragment (Product #RP-101485).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649128
Product Specific Information
Immunogen sequence: HQTGIHATEE LKEFFAKARA GSVRLIKVVI EDEQLVLGAS QEPVGRWDQD YDRAVLPLLD AQQPCYLLYR
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
Target Information
TWF2 encodes a protein that was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin, a conserved actin monomer-binding protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A6 related protein; A6-related protein; hA6RP; Protein tyrosine kinase 9-like; protein tyrosine kinase 9-like (A6-related protein); PTK 9L; PTK9L protein tyrosine kinase 9-like (A6-related protein); TWF 2; Twinfilin 2; twinfilin actin-binding protein 2; twinfilin, actin-binding protein, homolog 2; Twinfilin-1-like protein; Twinfilin-2; Twinfilin2
Gene Aliases: A6r; A6RP; MSTP011; PTK9L; TWF2
UniProt ID: (Human) Q6IBS0
Entrez Gene ID: (Human) 11344
positive regulation of lamellipodium assembly
positive regulation of neuron projection development
cell projection organization
negative regulation of actin filament polymerization
regulation of microvillus length
regulation of actin cytoskeleton organization
sequestering of actin monomers
positive regulation of axon extension
barbed-end actin filament capping
cellular response to retinoic acid
cellular response to growth factor stimulus
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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