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Invitrogen
TXNDC3 Polyclonal Antibody
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Product Details
PA5-53967
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TXNDC3. Recombinant protein control fragment (Product #RP-92279).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2649142
Product Specific Information
Immunogen sequence: AQLCDIEEDA ANVAKFMDAF FPDFKKMKSM KLEKTLALLR PNLFHERKDD VLRIIKDEDF KILEQRQVVL SEKEAQALCK EYENED
Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 55%.
Target Information
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exonuclease NME8; epididymis secretory protein Li 99; NM23-H8; NME/NM23 family member 8; sperm-specific thioredoxin 2; Spermatid-specific thioredoxin-2; Sptrx-2; thioredoxin domain containing 3 (spermatozoa); Thioredoxin domain-containing protein 3
Gene Aliases: CILD6; HEL-S-99; NM23-H8; NME8; sptrx-2; SPTRX2; TXNDC3
UniProt ID: (Human) Q8N427
Entrez Gene ID: (Human) 51314
nucleoside diphosphate phosphorylation
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
multicellular organism development
spermatogenesis
cell differentiation
sperm motility
cellular response to reactive oxygen species
cilium assembly
cell redox homeostasis
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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