Proteintech

TXNDC5 Polyclonal Antibody

TXNDC5 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 14

TXNDC5 Antibody (19834-1-AP) in ICC/IF

Immunofluorescent analysis of Hela cells, using TXNDC5 antibody 19834-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

TXNDC5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

19834-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:20,000-1:100,000

View 10 publications 10 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:10-1:100

View 3 publications 3 publications

Flow Cytometry (Flow)

View 1 publication 1 publication

Immunoprecipitation (IP)

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TXNDC5 Fusion Protein Ag13808 (109-432 aa encoded by BC001199)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEDAKVYVA KVDCTAHSDV CSAQGVRGYP TLKLFKPGQE AVKYQGPRDF QTLENWMLQT LNEEPVTPEP EVEPPSAPEL KQGLYELSAS NFELHVAQGD HFIKFFAPWC GHCKALAPTW EQLALGLEHS ETVKIGKVDC TQHYELCSGN QVRGYPTLLW FRDGKKVDQY KGKRDLESLR EYVESQLQRT ETGATETVTP SEAPVLAAEP EADKGTVLAL TENNFDDTIA EGITFIKFYA PWCGHCKTLA PTWEELSKKE FPGLAGVKIA EVDCTAERNI CSKYSVRGYP TLLLFRGGKK VSEHSGGRDL DSLHRFVLSQ AKDEL (109-432 aa encoded by BC001199)

Target Information

This gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo.

Science advances

Yeh CF,Cheng SH,Lin YS,Shentu TP,Huang RT,Zhu J,Chen YT,Kumar S,Lin MS,Kao HL,Huang PH,Roselló-Sastre E,Garcia F,Jo H,Fang Y,Yang KC

Fri Jan 21 00:00:00 UTC 2022

Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo.

Science advances

Yeh CF,Cheng SH,Lin YS,Shentu TP,Huang RT,Zhu J,Chen YT,Kumar S,Lin MS,Kao HL,Huang PH,Roselló-Sastre E,Garcia F,Jo H,Fang Y,Yang KC

Fri Jan 21 00:00:00 UTC 2022

Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo.

Science advances

Yeh CF,Cheng SH,Lin YS,Shentu TP,Huang RT,Zhu J,Chen YT,Kumar S,Lin MS,Kao HL,Huang PH,Roselló-Sastre E,Garcia F,Jo H,Fang Y,Yang KC

Fri Jan 21 00:00:00 UTC 2022

A comprehensive set of ER protein disulfide isomerase family members supports the biogenesis of proinflammatory interleukin 12 family cytokines.

The Journal of biological chemistry

Mideksa YG,Aschenbrenner I,Fux A,Kaylani D,Weiß CAM,Nguyen TA,Bach NC,Lang K,Sieber SA,Feige MJ

Thu Dec 01 00:00:00 UTC 2022

Squalene Loaded Nanoparticles Effectively Protect Hepatic AML12 Cell Lines against Oxidative and Endoplasmic Reticulum Stress in a TXNDC5-Dependent Way.

Antioxidants (Basel, Switzerland)

Bidooki SH,Alejo T,Sánchez-Marco J,Martínez-Beamonte R,Abuobeid R,Burillo JC,Lasheras R,Sebastian V,Rodríguez-Yoldi MJ,Arruebo M,Osada J

Fri Mar 18 00:00:00 UTC 2022

Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts.

The Journal of clinical investigation

Chen YT,Jhao PY,Hung CT,Wu YF,Lin SJ,Chiang WC,Lin SL,Yang KC

Mon Mar 01 00:00:00 UTC 2021

Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts.

The Journal of clinical investigation

Chen YT,Jhao PY,Hung CT,Wu YF,Lin SJ,Chiang WC,Lin SL,Yang KC

Mon Mar 01 00:00:00 UTC 2021

Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts.

The Journal of clinical investigation

Chen YT,Jhao PY,Hung CT,Wu YF,Lin SJ,Chiang WC,Lin SL,Yang KC

Mon Mar 01 00:00:00 UTC 2021

Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts.

The Journal of clinical investigation

Chen YT,Jhao PY,Hung CT,Wu YF,Lin SJ,Chiang WC,Lin SL,Yang KC

Mon Mar 01 00:00:00 UTC 2021

Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts.

The Journal of clinical investigation

Chen YT,Jhao PY,Hung CT,Wu YF,Lin SJ,Chiang WC,Lin SL,Yang KC

Mon Mar 01 00:00:00 UTC 2021

Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis.

International immunopharmacology

Chen X,Li C,Liu J,He Y,Wei Y,Chen J

Tue Jun 01 00:00:00 UTC 2021

Inhibition of ER stress by targeting the IRE1α-TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis.

International immunopharmacology

Chen X,Li C,Liu J,He Y,Wei Y,Chen J

Tue Jun 01 00:00:00 UTC 2021

m⁶A Methyltransferase METTL3 Promotes the Progression of Primary Acral Melanoma via Mediating TXNDC5 Methylation.

Frontiers in oncology

Yue Z,Cao M,Hong A,Zhang Q,Zhang G,Jin Z,Zhao L,Wang Q,Fang F,Wang Y,Sun J

Sun Nov 05 00:00:00 UTC 2023

Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization.

Nature communications