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Invitrogen
TXNIP Polyclonal Antibody
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FIGURE: 1 / 5
TXNIP Antibody (PA5-113961) in WB
Western Blot of Mouse mesenchymal stem cell lysate using a Polyclonal TXNIP Antibody (Product # PA5-113961). Lane 1: 20 µg mouse mesenchymal stem cell lysate. Primary antibody dilution: 1:2,000. Secondary antibody: Anti-rabbit-HRP. Secondary antibody dilution: 1:10,000.
Product Details
PA5-113961
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C terminal region of human TXNIP (aa 326-375).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2884476
Product Specific Information
Immunogen sequence: DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%
Target Information
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hyperlipidemia 1; thioredoxin binding protein 2; thioredoxin binding protein-2; Thioredoxin-binding protein 2; Thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; Vitamin D3 up-regulated protein 1
Gene Aliases: 1200008J08Rik; AA682105; ARRDC6; EST01027; HHCPA78; Hyplip1; Tbp-2; THIF; TXNIP; VDUP1
UniProt ID: (Human) Q9H3M7, (Mouse) Q8BG60
Entrez Gene ID: (Human) 10628, (Mouse) 56338
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
protein import into nucleus
cell cycle
response to mechanical stimulus
response to glucose
keratinocyte differentiation
response to estradiol
response to progesterone
regulation of cell proliferation
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
negative regulation of catalytic activity
platelet-derived growth factor receptor signaling pathway
response to calcium ion
negative regulation of cell division
cellular response to tumor cell
regulation of transcription, DNA-templated
response to oxidative stress
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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