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Invitrogen
TXNIP Recombinant Rabbit Monoclonal Antibody (JM60-35)
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FIGURE: 1 / 11
TXNIP Antibody (MA5-32771) in ICC/IF
Immunocytochemical analysis of TXNIP in SH-SY5Y cells using a TXNIP Monoclonal antibody (Product # MA5-32771) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32771
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JM60-35
Immunogen
Synthetic peptide within Human TXNIP aa 50-99
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2810048
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hyperlipidemia 1; thioredoxin binding protein 2; thioredoxin binding protein-2; Thioredoxin-binding protein 2; Thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; Vitamin D3 up-regulated protein 1
Gene Aliases: 1200008J08Rik; AA682105; ARRDC6; EST01027; HHCPA78; Hyplip1; Tbp-2; THIF; TXNIP; VDUP1
UniProt ID: (Human) Q9H3M7, (Rat) Q5M7W1, (Mouse) Q8BG60
Entrez Gene ID: (Human) 10628, (Rat) 117514, (Mouse) 56338
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
protein import into nucleus
cell cycle
response to mechanical stimulus
response to glucose
keratinocyte differentiation
response to estradiol
response to progesterone
regulation of cell proliferation
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
negative regulation of catalytic activity
platelet-derived growth factor receptor signaling pathway
response to calcium ion
negative regulation of cell division
cellular response to tumor cell
response to oxidative stress
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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