Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Positive Samples: SKOV3, Mouse heart
Immunogen sequence: MVGVKPVGSD PDFQPELSGA GSRLAVVKFT MRGCGPCLRI APAFSSMSNK YPQAVFLEVD VHQCQGTAAT NNISATPTFL FFRNKVRIDQ YQGADAVGLE EKIKQHLEND PGSNEDTDIP KGYMDLMPFI NKAGCECLNE SDEHGFDNCL RKDTTFLESD CDEQLLITVA FNQPVKLYSM KFQGPDNGQG PKYVKIFINL PRSMDFEEAE RSEPTQALEL TEDDIKEDGI VPLRYVKFQN VNSVTIFVQS NQGEEETTRI SYFTFIGTPV QATNMNDFKR VVGKKGESH
Thioredoxins are a group of small redox active proteins possessing a conserved active site sequence. TrxL (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43% identical to human TXN, and a C terminal domain, which shows no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein; compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TrxL does not serve as a substrate for thioredoxin reductase in an insulin assay.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 32 kDa thioredoxin-related protein; epididymis secretory protein Li 114; thioredoxin-like (32kD); thioredoxin-like 1; Thioredoxin-like protein 1; thioredoxin-related 32 kDa protein; Thioredoxin-related protein; thioredoxin-related protein 1
Gene Aliases: 32kDa; HEL-S-114; Trp; TRP32; TXL; TXL-1; TXNL; TXNL1
UniProt ID: (Human) O43396, (Rat) Q920J4, (Mouse) Q8CDN6
Entrez Gene ID: (Human) 9352, (Rat) 140922, (Mouse) 53382
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