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Product Details
17665-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TYW1B Fusion Protein Ag11947 (319-668 aa encoded by BC068520)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TKQVDAPRE RSLLQTHILW NESHRCMETT PSLACANKCV FCWWHHNNPV GTEWLWKMDQ PEMILKEAIE NHQNMIKQFK GVPGVKAERF EEGMTVKHCA LSLVGEPIMY PEINRFLKLL HQCKISSFLV TNAQFPAEIR NLEPVTQLYV SVDASTKDSL KKIDRPLFKD FWQQFLDSLK ALAVKQQRTV YRLTLVKAWN VDELQAYAQL VSLGNPDFIE VKGVTYCRES SASSLTMAHV PWHEEVVQFV RELVDLIPEY EIACEHEHSN CLLIAHRKFK IGGEWWTWID YNRFQELIQE YEDSGGSKTF SAKDYMARTP HWALFGANER SFDPKDTRHQ RKNKSKAISG C (319-668 aa encoded by BC068520)
Target Information
Wybutosine is a hypermodified guanosine found in phenylalanine tRNA. Wybutosine functions to stabilize codon-anticodon interactions during ribosome decoding and therefore supports the maintenance of the reading frame. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. [provided by RefSeq, Apr 2014].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: long intergenic non-protein coding RNA 69; MGC87315; Radical S-adenosyl methionine and flavodoxin domain-containing protein 2; radical S-adenosyl methionine and flavodoxin domains 1; S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B; tRNA wybutosine-synthesizing protein 1 homolog B; tRNA-yW synthesizing protein 1 homolog B (non-protein coding)
Gene Aliases: LINC00069; NCRNA00069; RSAFD2; TYW1B
UniProt ID: (Human) Q6NUM6
Entrez Gene ID: (Human) 441250
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