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Invitrogen
Tartrate Resistant Acid Phosphatase Polyclonal Antibody
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Tartrate Resistant Acid Phosphatase Antibody (PA5-116970) in IHC (P)
Immunohistochemistry (Immunofluorescence) analysis of Tartrate Resistant Acid Phosphatase in human lung cancer. Samples were incubated with Tartrate Resistant Acid Phosphatase Polyclonal antibody (Product # PA5-116970) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Product Details
PA5-116970
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 76-325 of human ACP5 (NP_0016021)
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2901600
Product Specific Information
Positive Samples: BT-474, Jurkat
Immunogen sequence: TGVQDINDKR FQETFEDVFS DRSLRKVPWY VLAGNHDHLG NVSAQIAYSK ISKRWNFPSP FYRLHFKIPQ TNVSVAIFML DTVTLCGNSD DFLSQQPERP RDVKLARTQL SWLKKQLAAA REDYVLVAGH YPVWSIAEHG PTHCLVKQLR PLLATYGVTA YLCGHDHNLQ YLQDENGVGY VLSGAGNFMD PSKRHQRKVP NGYLRFHYGT EDSLGGFAYV EISSKEMTVT YIEASGKSLF KTRLPRRARP
Target Information
Tartrate-resistant acid phosphatase (TRAP) is a basic iron-binding protein with high activity towards phosphoproteins, ATP and 4-nitrophenyl phosphatase. It is detected in human alveolar macrophages, osteoclasts, spleen and liver. Its expression is increased in spleen and monocytes of patients with Gaucher's disease; spleenocytes and circulating leukocytes of patients with hairy cell leukemia; spleen of patients with Hodgkin's lymphoma and in the sera of patients undergoing active bone turnover.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: acid phosphatase type V; human purple acid phosphatase; Tartrate-resistant acid ATPase; tartrate-resistant acid phosphatase 5a; tartrate-resistant acid phosphatase 5b; Tartrate-resistant acid phosphatase type 5; TR-AP; TRAPase; TrATPase; Type 5 acid phosphatase
Gene Aliases: ACP5; HPAP; TRACP5a; TRACP5b; TRAP; TrATPase; TTRRAP
UniProt ID: (Human) P13686, (Rat) P29288
Entrez Gene ID: (Human) 54, (Rat) 25732
ossification
riboflavin metabolic process
negative regulation of cell adhesion
response to zinc ion
dephosphorylation
osteoclast differentiation
positive regulation of cell migration
response to lipopolysaccharide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-12 production
negative regulation of tumor necrosis factor production
negative regulation of superoxide anion generation
multicellular organismal response to stress
response to L-ascorbic acid
response to cytokine
negative regulation of nitric oxide biosynthetic process
bone resorption
negative regulation of inflammatory response
defense response to Gram-positive bacterium
bone morphogenesis
response to cholesterol
metabolic process
response to organic cyclic compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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