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Invitrogen
Tenascin X Polyclonal Antibody
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FIGURE: 1 / 3
Tenascin X Antibody (PA5-46966) in IHC (P)
Immunohistochemical analysis of Tenascin X in immersion fixed paraffin-embedded sections of human lung mesothelioma. Samples were incubated in Tenascin X polyclonal antibody (Product # PA5-46966) using a dilution of 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to stro... View More
Product Details
PA5-46966
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHO-derived recombinant human Tenascin X isoform 2 Met1-Gly673
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609194
Product Specific Information
This antibody detects recombinant human Tenascin X isoform 2 in direct ELISAs and human Tenascin X in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human Tenascin R is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM). It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: growth-inhibiting protein 45; Hexabrachion-like protein; tenascin XB1; tenascin XB2; Tenascin-X; TN-X; TNXB2tenascin XB1; TNXBSTNXTENX; XB-S; XBTN-X
Gene Aliases: EDS3; HXBL; TENX; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; VUR8; XB; XBS
UniProt ID: (Human) P22105
Entrez Gene ID: (Human) 7148
fatty acid metabolic process
triglyceride metabolic process
cell adhesion
cell-matrix adhesion
single organismal cell-cell adhesion
actin cytoskeleton organization
collagen fibril organization
collagen metabolic process
extracellular fibril organization
regulation of JUN kinase activity
elastic fiber assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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