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Invitrogen
Tenascin X Polyclonal Antibody
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FIGURE: 1 / 1
Tenascin X Antibody (PA5-96155) in WB
Western blot analysis of Tenascin X in extracts of various cell lines. Samples were incubated with Tenascin X Polyclonal antibody (Product # PA5-96155) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-96155
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 444-673 of human TNXB (NP_1158592)
Conjugate
Form
Liquid
Concentration
2.02 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807957
Product Specific Information
Immunogen sequence: TSFTTGGLRI PFPRDCGEEM QNGAGASRTS TIFLNGNRER PLNVFCDMET DGGGWLVFQR RMDGQTDFWR DWEDYAHGFG NISGEFWLGN EALHSLTQAG DYSMRVDLRA GDEAVFAQYD SFHVDSAAEY YRLHLEGYHG TAGDSMSYHS GSVFSARDRD PNSLLISCAV SYRGAWWYRN CHYANLNGLY GSTVDHQGVS WYHWKGFEFS VPFTEMKLRP RNFRSPAGGG; Positive Samples: Mouse liver, Mouse kidney, Rat liver; Cellular Location: extracellular matrix, extracellular space
Target Information
Tenascin-X (TNXB) is a extracellular matrix glycoprotein predominantly located in the outer reticular lamina of the basement membrane (BM). It interacts with many other ECM proteins and it accelerates collagen fibrillogenesisin vitro. TNXB plays a role in interactions between cell and ECM, antiadhesive effect, inhibiting cell migration, and in maintaining homeostasis of the extracellular matrix. Deficiency of TNXB has been associated with the connective tissue disorder Ehlers-Danlos syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: tenascin-X; TNXB2tenascin XB1; TNXBSTNXTENX; XB-S; XBTN-X
Gene Aliases: Tn-mhc; Tnx
Entrez Gene ID: (Rat) 415089, (Mouse) 81877
lipid metabolic process
fatty acid metabolic process
triglyceride metabolic process
phospholipid metabolic process
cell-matrix adhesion
single organismal cell-cell adhesion
extracellular matrix organization
collagen fibril organization
collagen metabolic process
extracellular fibril organization
regulation of JUN kinase activity
positive regulation of cell adhesion
elastic fiber assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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