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Immunogen sequence: CFLAFTQTKT FHEASEDCIS RGGTLGTPQT GSENDALYEY LRQSVGNEAE IWLGLNDMAA EGTWVDMTGA RIAYKNWETE ITAQPDGGKT ENCAVLSGAA NGKWFDKRCR DQLPYICQFG IV; Positive Samples: LO2, 293T, Mouse liver
Tetranectin (TN) is a serum and tissue protein, a C-type lectin, which binds to Ca++. It is a homotrimer of monomers each with a mass of 20 kDa, plasma or serum concentrations of TN are found to be approximately 10 mg/l. In vitro, TN can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. TN is best known as a prognostic marker in ovarian cancer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type lectin domain family 3 member B; C-type lectin domain family 3, member B; Plasminogen kringle 4-binding protein; Tetranectin; tetranectin (plasminogen binding protein); tetranectin (plasminogen-binding protein); tetranectin-like; TN
Gene Aliases: CLEC3B; TN; TNA
UniProt ID: (Human) P05452
Entrez Gene ID: (Human) 7123, (Mouse) 21922, (Rat) 100912012
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