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Invitrogen
Thrombospondin 4 Polyclonal Antibody
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Product Details
PA5-68467
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human Thrombospondin 4 [aa 551-660].
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2688426
Product Specific Information
Predicted to react with Human samples.
Target Information
Thrombospondin-4 (THBS4) belongs to the thrombospondin protein family, a family of adhesive calcium-binding glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. Studies suggest that this protein may be involved in local signaling in the developing and adult nervous system. THBS4 is widely expressed and is abundant in atherosclerotic lesions and in areas prone to the development of lesions. It has been suggested to play an important role in the recruitment of macrophages and the local regulation of inflammation associated with atherogenesis. THBS4 has also been suggested as a putative tumor-suppressor protein in colorectal cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Thrombospondin-4
Gene Aliases: THBS4; TSP-4; TSP4
UniProt ID: (Human) P35443
Entrez Gene ID: (Human) 7060
positive regulation of endothelial cell proliferation
response to unfolded protein
negative regulation of angiogenesis
regulation of tissue remodeling
response to endoplasmic reticulum stress
behavioral response to pain
tissue remodeling
neuron projection morphogenesis
positive regulation of peptidyl-tyrosine phosphorylation
protein homooligomerization
myoblast migration
positive regulation of cell division
endothelial cell-cell adhesion
positive regulation of neutrophil chemotaxis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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