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          • Primary Antibodies ›
          • Thyroglobulin Antibodies

          NeoBiotechnologies

          Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (r6E1)

          View all (101) Thyroglobulin antibodies

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          Cite Thyroglobulin (Thyroidal Cell Marker) Monoclonal Antibody (r6E1)

          • Antibody Testing Data (3)
          Thyroglobulin (Thyroidal Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Thyroglobulin (Thyroidal Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

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          Thyroglobulin (Thyroidal Cell Marker) Antibody (7038-MSM9-P1ABX) in IHC (P)

          Formalin-fixed, paraffin-embedded human Thyroid stained with Thyroglobulin Mouse Recombinant Monoclonal Antibody (r6E1). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Thyroglobulin (Thyroidal Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Thyroglobulin (Thyroidal Cell Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Thyroglobulin (Thyroidal Cell Marker) Antibody in SDS-PAGE (SDS-PAGE)

          Product Details

          7038-MSM9-P1ABX

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          0.25-0.5 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          r6E1

          Immunogen

          Human thyroid follicular cells
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A/G

          Storage buffer

          PBS, pH 7.4

          Contains

          no preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Does not react with Mouse or Rat

          Target Information

          The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Colloid; Tg; Thyroglobulin

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          Gene Aliases: AITD3; TG; TGN

          View more View less

          UniProt ID: (Human) P01266

          View more View less

          Entrez Gene ID: (Human) 7038

          View more View less

          Function(s)
          hormone activity protein complex binding protein homodimerization activity anion binding chaperone binding carboxylic ester hydrolase activity
          Process(es)
          thyroid hormone generation signal transduction response to pH iodide transport thyroid gland development regulation of myelination response to lipopolysaccharide hormone biosynthetic process transcytosis
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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