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Proteintech
Torsin A Polyclonal Antibody
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Product Details
10296-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Torsin A Fusion Protein Ag0358 (32-304 aa encoded by BC000674)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GVLTGYIYP RLYCLFAECC GQKRSLSREA LQKDLDDNLF GQHLAKKIIL NAVFGFINNP KPKKPLTLSL HGWTGTGKNF VSKIIAENIY EGGLNSDYVH LFVATLHFPH ASNITLYKDQ LQLWIRGNVS ACARSIFIFD EMDKMHAGLI DAIKPFLDYY DLVDGVSYQK AMFIFLSNAG AERITDVALD FWRSGKQRED IKLKDIEHAL SVSVFNNKNS GFWHSSLIHR NLIDYFVPFL PLEYKHLKMC IRVEMQSRGY EIDEDIVSRV AEEM (32-304 aa encoded by BC000674)
Target Information
The protein encoded by this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family and is expressed prominently in the substantia nigra pars compacta. Mutations in this gene result in the autosomal dominant disorder, torsion dystonia 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dystonia 1; Dystonia 1 protein; Dystonia 1 torsion; dystonia 1, torsion (autosomal dominant; dystonia 1, torsion (autosomal dominant; torsin A); Torsin 1A; torsin A; Torsin ATPase 1; Torsin ATPase-1A; Torsin family 1 member A; torsin family 1, member A (torsin A); Torsin-1A
Gene Aliases: DQ2; DYT1; TA; TOR1A; TORA; torsinA
UniProt ID: (Human) O14656, (Rat) Q68G38, (Mouse) Q9ER39
Entrez Gene ID: (Human) 1861, (Rat) 266606, (Mouse) 30931
protein deneddylation
response to oxidative stress
organelle organization
nuclear envelope organization
cell adhesion
neuron projection development
protein localization to nucleus
wound healing, spreading of cells
intermediate filament cytoskeleton organization
synaptic vesicle transport
chaperone mediated protein folding requiring cofactor
protein homooligomerization
regulation of dopamine uptake involved in synaptic transmission
chaperone-mediated protein folding
ER-associated misfolded protein catabolic process
nuclear membrane organization
chaperone-mediated protein transport
positive regulation of synaptic vesicle endocytosis
regulation of protein localization to cell surface
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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