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Alomone Labs, LTD
Trace Amine Receptor 1 (TAAR1) Polyclonal Antibody
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FIGURE: 1 / 1
Trace Amine Receptor 1 (TAAR1) Antibody (ATR-021-200UL) in WB
Western blot analysis of rat liver (lane 1 and 4), mouse kidney (lanes 2 and 5) and human brain glioblastoma (U-87) cell (lanes 3 and 6) lysates: - 1-3. Anti-Trace Amine Receptor 1 (TAAR1) Antibody (#ATR-021), (1:200).4-6. Anti-Trace Amine Receptor 1 (TAAR1) Antibody , preincubated with Trace Amine Receptor 1/TAAR1 Blocking Peptide (#BLP-TR021).
Product Details
ATR-021-200UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)KMVLFGKIFQKDS, corresponding to amino acid residues 313-325 of rat TAAR1, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
Target Information
TA1 has been reported in human brain, dorsal root ganglion, olfactory bulb, kidney, liver, lung, pancreas, prostate, skeletal muscle, small intestine, spleen, spinal cord, and stomach. An EST for TA1 has been identified from a human stomach cancer library. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC126874; MGC138399; RP11-295F4.9; RTAR1; Snorf33; TaR-1; trace amine receptor 1; Trace amine-associated receptor 1
Gene Aliases: TA1; TAAR1; taR-1; TAR1; TRAR1
UniProt ID: (Human) Q96RJ0, (Rat) Q923Y9, (Mouse) Q923Y8
Entrez Gene ID: (Human) 134864, (Rat) 113914, (Mouse) 111174
G-protein coupled receptor signaling pathway
cAMP biosynthetic process
signal transduction
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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