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Invitrogen
Transferrin Recombinant Rabbit Monoclonal Antibody (005)
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Product Details
MA5-29871
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
005
Immunogen
Recombinant Rat Transferrin/TF Protein (Met1-Ser698)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785688
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Rat Transferrin/TF.
Target Information
Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; Liver regeneration-related protein LRRG03; Serotransferrin; Siderophilin; transferin; Transferrin
Gene Aliases: Tf; Tfn; Trf
UniProt ID: (Rat) P12346
Entrez Gene ID: (Rat) 24825
response to hypoxia
retina homeostasis
iron ion transport
cellular iron ion homeostasis
apoptotic process
acute-phase response
actin filament organization
activation of JUN kinase activity
small GTPase mediated signal transduction
response to lead ion
response to organic cyclic compound
ferric iron transport
osteoclast differentiation
positive regulation of myelination
positive regulation of phosphorylation
positive regulation of bone resorption
positive regulation of transcription, DNA-templated
SMAD protein signal transduction
ERK1 and ERK2 cascade
positive regulation of oligodendrocyte progenitor proliferation
cellular response to cAMP
cellular response to follicle-stimulating hormone stimulus
positive regulation of cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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