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Trefoil factor 1 Polyclonal Antibody

Trefoil factor 1 Antibody in Immunocytochemistry (ICC/IF)

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Trefoil factor 1 Antibody (13734-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 13734-1-AP (Trefoil factor 1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

Trefoil factor 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Trefoil factor 1 Antibody in Western Blot (WB)

Product Image Gallery

Product Details

13734-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Trefoil factor 1 Fusion Protein Ag4541 (1-84 aa encoded by BC032811)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MATMENKVI CALVLVSMLA LGTLAEAQTE TCTVAPRERQ NCGFPGVTPS QCANKGCCFD DTVRGVPWCF YPNTIDVPPE EECEF (1-84 aa encoded by BC032811)

Target Information

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer.

Cell death and differentiation

Sun G,Wei Y,Zhou B,Wang M,Luan R,Bai Y,Li H,Wang S,Zheng D,Wang C,Wang S,Zeng K,Liu S,Lin L,He M,Zhang Q,Zhao Y

Mon May 01 00:00:00 UTC 2023

Resolving the difference between left-sided and right-sided colorectal cancer by single-cell sequencing.

JCI insight

Guo W,Zhang C,Wang X,Dou D,Chen D,Li J

Tue Jan 11 00:00:00 UTC 2022

Cell-Free Fat Extract Prevents Vaginal Atrophy in an Ovariectomized Model by Promoting Proliferation of Vaginal Keratinocytes and Neovascularization.

Aesthetic surgery journal

Kang B,Cai Y,Jia Z,Chen C,Deng M,Zhang W,Li W

Sat Jan 01 00:00:00 UTC 2022

Trefoil factor-1 upregulation in estrogen-receptor positive breast cancer correlates with an increased risk of bone metastasis.

Bone

Spadazzi C,Mercatali L,Esposito M,Wei Y,Liverani C,De Vita A,Miserocchi G,Carretta E,Zanoni M,Cocchi C,Bongiovanni A,Recine F,Kang Y,Ibrahim T

Mon Mar 01 00:00:00 UTC 2021

Trefoil factor-1 upregulation in estrogen-receptor positive breast cancer correlates with an increased risk of bone metastasis.

Bone

Spadazzi C,Mercatali L,Esposito M,Wei Y,Liverani C,De Vita A,Miserocchi G,Carretta E,Zanoni M,Cocchi C,Bongiovanni A,Recine F,Kang Y,Ibrahim T

Mon Mar 01 00:00:00 UTC 2021

A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.

Cell death discovery

Li P,Cao S,Huang Y,Zhang Y,Liu J,Cai X,Zhou L,Li J,Jiang Z,Ding L,Zheng Z,Li S,Ye Q

Thu Jul 29 00:00:00 UTC 2021

Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine.

The Journal of experimental medicine

Wang Y,Song W,Wang J,Wang T,Xiong X,Qi Z,Fu W,Yang X,Chen YG

Mon Feb 03 00:00:00 UTC 2020

Trefoil factor 1 (TFF1) is a potential prognostic biomarker with functional significance in breast cancers.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yi J,Ren L,Li D,Wu J,Li W,Du G,Wang J

Wed Apr 01 00:00:00 UTC 2020

Trefoil factor 1 (TFF1) is a potential prognostic biomarker with functional significance in breast cancers.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Yi J,Ren L,Li D,Wu J,Li W,Du G,Wang J

Wed Apr 01 00:00:00 UTC 2020

MORC2 regulates C/EBPα-mediated cell differentiation via sumoylation.

Cell death and differentiation

Liu J,Zhang Q,Ruan B,Chen W,Zheng J,Xu B,Jiang P,Miao Z,Li F,Guo JY,Cao L,Wang G

Tue Oct 01 00:00:00 UTC 2019

MORC2 regulates C/EBPα-mediated cell differentiation via sumoylation.

Cell death and differentiation

Liu J,Zhang Q,Ruan B,Chen W,Zheng J,Xu B,Jiang P,Miao Z,Li F,Guo JY,Cao L,Wang G

Tue Oct 01 00:00:00 UTC 2019

Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.

International journal of clinical and experimental pathology

Zhao S,Ma Y,Huang X

Wed Sep 28 00:00:00 UTC 2016

Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.

International journal of clinical and experimental pathology

Zhao S,Ma Y,Huang X

Wed Sep 28 00:00:00 UTC 2016

Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.

International journal of clinical and experimental pathology

Zhao S,Ma Y,Huang X

Wed Sep 28 00:00:00 UTC 2016

Trefoil factor 1 elevates the malignant phenotype of mucinous ovarian cancer cell through Wnt/β-catenin signaling.

International journal of clinical and experimental pathology

Zhao S,Ma Y,Huang X

Wed Sep 28 00:00:00 UTC 2016

Distinctions in gastric cancer gene expression signatures derived from laser capture microdissection versus histologic macrodissection.

BMC medical genomics

Kim HK,Kim J,Korolevich S,Choi IJ,Kim CH,Munroe DJ,Green JE

Thu Jun 02 00:00:00 UTC 2011

Distinctions in gastric cancer gene expression signatures derived from laser capture microdissection versus histologic macrodissection.

BMC medical genomics

Kim HK,Kim J,Korolevich S,Choi IJ,Kim CH,Munroe DJ,Green JE

Thu Jun 02 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: Breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; gastrointestinal trefoil protein pS2; hP1.A; PNR-2; Polypeptide P1.A; Protein pS2; Trefoil factor 1

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Gene Aliases: BCEI; D21S21; HP1.A; HPS2; pNR-2; PS2; TFF1

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UniProt ID: (Human) P04155, (Mouse) Q08423, (Rat) Q63467

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Entrez Gene ID: (Human) 7031, (Mouse) 21784, (Rat) 117270

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Function(s)

protein binding growth factor activity

Process(es)

carbohydrate metabolic process digestion negative regulation of cell proliferation response to iron ion cell differentiation maintenance of gastrointestinal epithelium response to immobilization stress response to peptide hormone response to wounding response to estradiol wound healing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Trefoil factor 1 Polyclonal Antibody

Trefoil factor 1 Antibody (13734-1-AP) in ICC/IF

Product Details

13734-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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