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This gene encodes a membrane protein that mediates cell adhesion between trophoblastic cells and the epithelial cells of the endometrium. The encoded protein participates in cell signalling during embryo implantation, and may also be involved in cancer formation. This gene is located near several other closely related genes on chromosome X. Alternative splicing results in multiple transcript variants.
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Protein Aliases: MAGE superfamily protein; MAGE-D3 antigen; magphinin; melanoma antigen, family D, 3; Trophinin
Gene Aliases: KIAA1114; MAGE-d3; MAGED3; TRO
UniProt ID: (Human) Q12816
Entrez Gene ID: (Human) 7216
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