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In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) TPSB2 is observed, 5% cross-reactivity with rhTPS1 is observed, and less than 1% cross-reactivity with rhTPSG1 and recombinant mouse MCPT1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Tryptase is a protein that belongs to the family of serine proteases and is primarily found in mast cells. It plays a crucial role in the immune response by cleaving and activating other proteins involved in inflammation and tissue repair. Tryptase is also involved in the regulation of blood pressure and has been implicated in various diseases, including asthma, allergies, and cardiovascular disorders. Its structure consists of four identical subunits that form a tetramer, and it is activated by proteolytic cleavage of its proenzyme form.
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Protein Aliases: Mast cell protease 7; mast cell-restricted serine protease 7; mMCP-7; TPSG1/TPSB2/TPSAB1/TPSD1; Tryptase; Tryptase alpha/beta-1
Gene Aliases: Mcp-7; Mcp7; Mcpt7; MMCP-7; Tpsab1
UniProt ID: (Mouse) Q02844
Entrez Gene ID: (Mouse) 100503895
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