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Invitrogen
UBC9 Recombinant Rabbit Monoclonal Antibody (SAIC-36A-9)
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FIGURE: 1 / 2
UBC9 Antibody (MA5-47917) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of UBC9 in Jurkat cells using UBC9 Recombinant Monoclonal Antibody (Product # MA5-47917). Paraformaldehyde-fixed cells were immobilized on a coverslip and stained with UBC9 Recombinant Monoclonal Antibody at a 1:100 dilution for 1h followed by Alexa Fluor 488 secondary antibody (1:1,000 dilution), showing nuclear staining. Actin filaments were stained with phalloidin (red) and the nuclear stain is DAPI (blue). Panels show from left-right, top-bottom UBC9 Recombinant Monoclonal Antibody, DAPI,... View More
Product Details
MA5-47917
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SAIC-36A-9
Immunogen
Peptide "DHPFGFVAVPTK", derived from the SUMO-conjugating enzyme UBC9, conjugated to KLH.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3074361
Product Specific Information
Specificity: Recognises human UBE2I.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000198131; p18; RING-type E3 SUMO transferase UBC9; SUMO-1-protein ligase; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; ubiquitin conjugating enzyme 9; ubiquitin conjugating enzyme E2I; Ubiquitin-conjugating enzyme E2 I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; Ubiquitin-protein ligase I
Gene Aliases: C358B7.1; P18; UBC9; UBCE9; UBE2I
UniProt ID: (Human) P63279
Entrez Gene ID: (Human) 7329
negative regulation of transcription from RNA polymerase II promoter
cellular protein modification process
ubiquitin-dependent protein catabolic process
chromosome segregation
mitotic nuclear division
viral process
protein sumoylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
cell division
global genome nucleotide-excision repair
positive regulation of SUMO transferase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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