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Product Details
PA5-80201
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human Diubiquitin (27-40aa YDSVKKIKEHVRSK).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2747315
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: HELA Cell, SKOV Cell, MCF-7 Cell, A549 Cell, SMMC Cell. IHC: Human Intestinal Cancer Tissue, Human Tonsil Tissue.
Target Information
UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Diubiquitin; UBD 3; Ubiquitin D; Ubiquitin-like protein FAT10
Gene Aliases: FAT10; GABBR1; UBD; UBD-3
UniProt ID: (Human) O15205
Entrez Gene ID: (Human) 10537
proteolysis
ubiquitin-dependent protein catabolic process
response to organonitrogen compound
protein ubiquitination
protein modification by small protein conjugation
response to interferon-gamma
response to tumor necrosis factor
myeloid dendritic cell differentiation
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
aggresome assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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