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Invitrogen
UBD Recombinant Rabbit Monoclonal Antibody (10A6T5)
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FIGURE: 1 / 3
UBD Antibody (MA5-35744) in ICC/IF
Confocal imaging (Immunocytochemistry) of UBD in NIH/3T3 cells. Samples were incubated with UBD Monoclonal antibody (Product # MA5-35744) using a dilution of 1:100 (Red). The cells were counterstained with alpha Tubulin Mouse mAb (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
Product Details
MA5-35744
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
10A6T5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human FAT10/UBD (O15205)
Conjugate
Form
Liquid
Concentration
2.8 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849644
Product Specific Information
Immunogen sequence: KEKTIHLTLK VVKPSDEELP LFLVESGDEA KRHLLQVRRS SSVAQVKAMI ETKTGIIPET QIVTCNGKRL EDGKMMADYG I
Target Information
UBD qualifies as a marker for an interferon response in hepatocellular carcinoma and colon carcinoma but is not significantly overexpressed in cancers lacking a proinflammatory environment. Immunohistochemical studies demonstrated increased UBD expression in HIV-associated nephropathy and in autosomal dominant polycystic kidney disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Diubiquitin; UBD 3; Ubiquitin D; Ubiquitin-like protein FAT10
Gene Aliases: FAT10; GABBR1; UBD; UBD-3
UniProt ID: (Human) O15205, (Rat) Q921A3, (Mouse) P63072
Entrez Gene ID: (Human) 10537, (Rat) 29168, (Mouse) 24108
ubiquitin-dependent protein catabolic process
response to organonitrogen compound
protein ubiquitination
response to interferon-gamma
response to tumor necrosis factor
myeloid dendritic cell differentiation
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
aggresome assembly
proteolysis
protein modification by small protein conjugation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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