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Invitrogen
UBE2D2 Polyclonal Antibody
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Product Details
PA5-86740
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide, corresponding to amino acids 102-147 of Human UBE2D2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2803500
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: (E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; E2(17)KB 2; p53-regulated ubiquitin-conjugating enzyme 1; ubc2e ubiquitin conjugating enzyme; Ubiquitin carrier protein D2; ubiquitin conjugating enzyme 2e; ubiquitin conjugating enzyme E2D 2; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Ubiquitin-protein ligase D2
Gene Aliases: 1500034D03Rik; E2(17)KB2; E217kB; PUBC1; Ubc2e; UBC4; UBC4/5; UBC5B; UBCH4; UBCH5B; UBE2D2; Ube2d2a
UniProt ID: (Human) P62837, (Mouse) P62838
Entrez Gene ID: (Human) 7322, (Rat) 641452, (Mouse) 56550
protein polyubiquitination
protein ubiquitination
protein autoubiquitination
protein K48-linked ubiquitination
metabolic process
stimulatory C-type lectin receptor signaling pathway
cellular protein modification process
ubiquitin-dependent protein catabolic process
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
T cell receptor signaling pathway
regulation of transcription from RNA polymerase II promoter in response to hypoxia
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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