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Proteintech
UBE2F Polyclonal Antibody
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Product Details
17056-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBE2F Fusion Protein Ag10764 (1-185 aa encoded by BC010549)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLTLASKLK RDDGLKGSRT AATASDSTRR VSVRDKLLVK EVAELEANLP CTCKVHFPDP NKLHCFQLTV TPDEGYYQGG KFQFETEVPD AYNMVPPKVK CLTKIWHPNI TETGEICLSL LREHSIDGTG WAPTRTLKDV VWGLNSLFTD LLNFDDPLNI EAAEHHLRDK EDFRNKVDDY IKRYAR (1-185 aa encoded by B C010549)
Target Information
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC18120; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2; NEDD8-conjugating enzyme UBE2F; RING-type E3 NEDD8 transferase UBE2F; ubiquitin conjugating enzyme E2F (putative); Ubiquitin-conjugating enzyme E2 F; ubiquitin-conjugating enzyme E2F (putative)
Gene Aliases: 2510010F15Rik; AI851109; NCE2; RGD1307608; UBE2F; Ube2fa
UniProt ID: (Human) Q969M7, (Rat) Q5U203, (Mouse) Q9CY34
Entrez Gene ID: (Human) 140739, (Rat) 363284, (Mouse) 67921
protein binding
ATP binding
ligase activity
NEDD8 transferase activity
ubiquitin protein ligase binding
ubiquitin protein ligase activity
ubiquitin-like protein transferase activity
nucleotide binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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