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This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 82%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (E3-independent) E2 ubiquitin-conjugating enzyme H; E2 ubiquitin-conjugating enzyme H; UBCH2; Ubiquitin carrier protein H; Ubiquitin-conjugating enzyme E2 H; Ubiquitin-conjugating enzyme E2-20K; Ubiquitin-protein ligase H
Gene Aliases: 1500009C23Rik; AI181839; AI326965; AI462483; AW227540; E2-20K; Gid3; N28148; Ubc8; Ube2h
UniProt ID: (Mouse) P62257
Entrez Gene ID: (Mouse) 22214
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