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Invitrogen
UBE2L6 Polyclonal Antibody
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UBE2L6 Antibody (PA5-120886) in IHC (P)
Immunohistochemistry analysis of UBE2L6 in paraffin-embedded human breast cancer using. Samples were incubated with UBE2L6 Polyclonal antibody (Product # PA5-120886) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-120886
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-153 of human UBE2L6 (NP_0042141)
Conjugate
Form
Liquid
Concentration
2.1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914458
Product Specific Information
Positive test controls include: Mouse spleen.
Immunogen sequence: KTCQVLEALN VLVNRPNIRE PLRMDLADLL TQNPELFRKN AEEFTLRFGV DRPS
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2 ubiquitin conjugating enzyme; E2 ubiquitin-conjugating enzyme L6; MGC40331; retinoic acid induced gene B protein; Retinoic acid-induced gene B protein; RIG-B; UbcH8; UbcM8; Ubiquitin carrier protein L6; ubiquitin conjugating enzyme E2L 6; ubiquitin-conjugating enzyme 8; ubiquitin-conjugating enzyme E2L 6; Ubiquitin-protein ligase L6; Ubiquitin/ISG15-conjugating enzyme E2 L6
Gene Aliases: 2810489I21Rik; RIG-B; Ubce8; UBCH8; Ubcm8; UBE2L6
UniProt ID: (Human) O14933, (Mouse) Q9QZU9
Entrez Gene ID: (Human) 9246, (Mouse) 56791
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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