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Immunogen sequence: MFLTVKLLL GQRCSLKVSG QESVATLKRL VSRRLKVPEE QQHLLFRGQL LEDDKHLSDY CIGPNASINV IMQPLEKMAL KEAHQPQTQP LWHQLGLVLA KHFEPQDAKA VLQLLRQEHE ERLQKISLEH LEQLAQYLLA EEPHVEPAGE RELEAKARPQ SSCDMEEKEE AAADQ (1-174 aa encoded by BC058929)
Ubiquitin is a 77 amino acid protein that targets proteins for degradation by the 26S proteasome. Ubiquitin-like proteins are not directly involved in protein degradation, but appear to have many mechanistic similarities with the ubiquitin pathway. UBL4B (Ubiquitin-like protein 4B) is a 174 amino acid cytoplasmic protein that contains a ubiquitin-like domain. UBL4B likely arose by retroposition during mammalian evolution from UBL4A, an X-linked intron-bearing housekeeping gene. While UBL4A is highly conserved, UBL4B has undergone rapid evolution and may have evolved new functions. Expression of UBL4B is restricted to post-meiotic germ cells in testis and ovarian tissue, where it likely functions in post-translational protein modification.
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Protein Aliases: FLJ25690; ubiquitin-like 4B; Ubiquitin-like protein 4B
Gene Aliases: 4930522D07Rik; UBL4B
UniProt ID: (Human) Q8N7F7, (Mouse) Q9CQ84
Entrez Gene ID: (Rat) 103691676, (Human) 164153, (Mouse) 67591
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