Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: MAENGESSG PPRPSRGPAA AQGSAAAPAE PKIIKVTVKT PKEKEEFAVP ENSSVQQFKE AISKRFKSQT DQLVLIFAGK ILKDQDTLIQ HGIHDGLTVH LVIKSQNRPQ GQSTQPSNAA GTNTTSASTP RSNSTPISTN SNPFGLGSLG GLAGLSSLGL SSTNFSELQS QMQQQLMASP EMMIQIMENP FVQSMLSNPD LMRQLIMANP QMQQLIQRNP EISHLLNNPD IMRQTLEIAR NPAMMQEMMR NQDLALSNLE SIPGGYNALR RMYTDIQEPM LNAAQEQFGG NPFASVGSSS SSGEGTQPSR TENRDPLPNP WAPPPATQSS ATTSTTTSTG SGSGNSSSNA TGNTVAAANY VASIFSTPGM QSLLQQITEN PQLIQNMLSA PYMRSMMQSL SQNPDLAAQM MLNSPLFTAN PQLQEQMRPQ LPAFLQQMQN PDTLSAMSNP RAMQALMQIQ QGLQTLATEA PGLIPSFTPG VGVGVLGTAI GPVGPVTPIG PIGPIVPFTP IGPIGPIGPT GPAAPPGSTG SGGPTGPTVS SAAPSETTSP TSESGPNQQF IQQMVQALAG ANAPQLPNPE VRFQQQLEQL NAMGFLNREA NLQALIATGG DINAAIERLL GSQPS (1-624 aa encoded by BC069237)
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.
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Protein Aliases: Chap1; DSK2 homolog; Nedd4 binding protein 4; PLIC-2; Protein linking IAP with cytoskeleton 2; Ubiquilin-2; Ubiquitin-like product Chap1/Dsk2
Gene Aliases: ALS15; CHAP1; DSK2; HRIHFB2157; N4BP4; PLIC2; RGD1563566; UBQLN2
UniProt ID: (Human) Q9UHD9
Entrez Gene ID: (Human) 29978, (Rat) 317396
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