Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: WTSTHGGSGS RQGRQDGDQD APDIRNRFPN FLGIIRLYDY LQQLHENPQS LGTYLQGTAS ALSQSQEPPP SVNRVPPSSP SSQEPGSGQP LPEESVAIKG RSSCPAFLRY PTENSTGQGG DQDGAGKSST GHSTNLPDLV SGLGDSANRV PFAPLSFSPT AAIPGIPEPP WLPSPAYPRS LRPDGMNPAP QLQDEIQPQL PLLMHLQAAM ANPRALQALR QIEQGLQVLA TEAPRLLLWF MPCLAGTGSV AGGIESREDP LMSEDPLPNP PPEVFPALDS AELGFLSPPF LHMLQDLVST NPQQLQPEAH FQVQL
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.
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Protein Aliases: testicular tissue protein Li 220; Ubiquilin-3
Gene Aliases: 4933400K24Rik; TUP-1; UBQLN3
UniProt ID: (Human) Q9H347, (Mouse) Q8C5U9
Entrez Gene ID: (Human) 50613, (Mouse) 244178, (Rat) 308905
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