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Product Details
13109-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBXN11 Fusion Protein Ag3772 (1-324 aa encoded by BC038106)
Conjugate
Form
Liquid
Concentration
0.47 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSPLASLS KTRKVPLPSE PMNPGRRGIR IYGDEDEVDM LSDGCGSEEK ISVPSCYGGI GAPVSRQVPA SHDSELMAFM TRKLWDLEQQ VKAQTDEILS KDQKIAALED LVQTLRPHPA EATLQRQEEL ETMCVQLQRQ VREMERFLSD YGLQWVGEPM DQEDSESKTV SEHGERDWMT AKKFWKPGDS LAPPEVDFDR LLASLQDLSE LVVEGDTQVT PVPGGARLRT LEPIPLKLYR NGIMMFDGPF QPFYDPSTQR CLRDILDGFF PSELQRLYPN GVPFKVISCS SNHTFGDFEG SGDTQPPQTP PILRGSRCTP WGTPV (1-324 aa encoded by BC038106)
Target Information
This gene encodes a protein with a divergent C-terminal UBX domain. The homologous protein in the rat interacts with members of the Rnd subfamily of Rho GTPases at the cell periphery through its C-terminal region. It also interacts with several heterotrimeric G proteins through their G-alpha subunits and promotes Rho GTPase activation. It is proposed to serve a bidirectional role in the promotion and inhibition of Rho activity through upstream signaling pathways. The 3' coding sequence of this gene contains a polymoprhic region of 24 nt tandem repeats. Several transcripts containing between 1.5 and five repeat units have been reported. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Colorectal tumor-associated antigen COA-1; colorectal tumor-associated antigen-1; Socius; UBX domain containing 5; UBX domain-containing protein 11; UBX domain-containing protein 5
Gene Aliases: 4930506L07Rik; COA-1; D4Bwg1540e; PP2243; SOC; SOCI; UBXD5; UBXN11
UniProt ID: (Human) Q5T124, (Rat) Q8R512, (Mouse) Q9D572
Entrez Gene ID: (Human) 91544, (Rat) 192207, (Mouse) 67586
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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